Milestone™ Herbicide – Frequently Asked Questions

If you don’t find the answers to your specific questions on Milestone™ herbicide here, feel free to Ask Our Experts.

What is Milestone™ herbicide?
What is the active ingredient in Milestone?
How does Milestone work?
What weeds does Milestone control?
Do I need to tank-mix Milestone with other herbicides?
What are the use rates for Milestone?
Where can I use Milestone™ herbicide?
Do I need a license to buy Milestone?
Do I need to remove my livestock from treated areas during or immediately after application?
Does Milestone stay where you spray it?
How fast does Milestone work, and how long does the control last?
How long before expected rainfall do I need to apply Milestone?
Can I spray Milestone under trees?
Will plants become resistant to Milestone™ herbicide?
What is the environmental impact of Milestone?
What is the EPA’s Reduced Risk Pesticide initiative?

What is Milestone™ herbicide?

Milestone™ herbicide is a new liquid formulation herbicide from Dow AgroSciences designed and developed specifically for use on rangeland and pastures to control noxious and invasive broadleaf species and other problem weeds.

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What is the active ingredient in Milestone?

The active ingredient in Milestone herbicide is aminopyralid, a new pyridine carboxylic acid herbicide. Aminopyralid emerged through Dow AgroSciences’ discovery and R&D programs and was developed specifically for the management of noxious and invasive broadleaf species. It provides broad-spectrum broadleaf weed control at very low labeled use rates (4 to 7 fl oz/acre, or 0.06 to 0.1 lb ae/acre), compared to currently registered herbicides with the same mode of action, including 2,4-D, clopyralid, triclopyr, picloram and dicamba.

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How does Milestone work?

Milestone™ herbicide translocates throughout the entire plant and accumulating in meristematic tissues, including the roots. It disrupts plant growth metabolic pathways affecting the growth process of the plant. This disruption of plant growth processes results in the control of susceptible plant species.

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What weeds does Milestone control?

Milestone provides consistent and dependable control of noxious and invasive broadleaf species, such as musk thistle, Canada thistle, knapweeds, yellow starthistle and tropical soda apple. Field trials have shown that Milestone does so with little or no injury to desirable cool- and warm-season grasses. See the product label for a complete list of weeds controlled.

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Do I need to tank-mix Milestone with other herbicides?

Used alone, Milestone™ herbicide applied at labeled rates controls many invasive weed species. If there is a need to broaden the spectrum of weeds controlled, Milestone is an excellent tank-mix partner with other herbicides, such as Remedy®, Surmount™ or PastureGard® herbicide or 2,4-D. When tank-mixing, use only in accordance with the most restrictive precautions and limitations on the respective product labels and always perform a jar test to ensure the compatibility of the products being used.

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What are the use rates for Milestone?

Milestone contains 2 pounds of active ingredient per gallon. Labeled weeds can be controlled at rates from 4 to 7 fluid ounces per acre (0.06 to 0.1 lb of aminopyralid/acre). Milestone controls many key species at rates substantially lower than currently registered herbicides.

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Where can I use Milestone™ herbicide?

While Dow AgroSciences developed Milestone specifically for rangeland and pasture use, it is an excellent weed management tool on other land types and is labeled for use on areas such as wildlife and habitat management areas; wildlife openings; natural areas, including wildlands and wildlife refuges; and around seasonally dry wetlands, including ditchbanks, dry ditches and dry canals. In addition, it can be applied up to the water’s edge, making it ideal for controlling weeds along creeks and streams and around stock ponds.

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Do I need a license to buy Milestone?

Milestone is not a federally Restricted Use Pesticide, so in most states, you do not need a license to purchase or apply Milestone herbicide. Check with your Cooperative Extension office or state department of agriculture for any local requirements.

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Do I need to remove my livestock from treated areas during or immediately after application?

There are no grazing (or haying) restrictions for any class of livestock, including beef cattle and lactating dairy animals, horses, sheep, goats and other livestock, animals or wildlife, with Milestone. Do not transfer grazing animals (including horses) from areas treated with Milestone™ herbicide to areas where sensitive broadleaf crops grow without first allowing 3 days of grazing on an untreated pasture. Otherwise, urine and manure may contain enough active ingredient to cause injury to sensitive broadleaf plants.

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Does Milestone stay where you spray it?

Because of its formulation, Milestone is essentially non-volatile. However, whether applying by ground or by air, users still must take precautions so that spray drift does not occur. And because of its low use rate, there is a low potential for runoff.

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How fast does Milestone work, and how long does the control last?

Milestone is primarily a postemergence herbicide, but it has excellent preemergence soil residual activity on many important weeds (see label for a complete list). Milestone™ herbicide can be applied to weeds at any stage of growth, but specific weeds may have optimal growth stages for control (see label). Within hours or days of application, the stems and leaves of many labeled weeds will stop growing and turn brown. Most annual susceptible weeds will be controlled within four to eight weeks after application; however, complete control of main stems and roots may take longer. Because of its residual activity, control can last all season long, or into the season after application on certain weed species.

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How long before expected rainfall do I need to apply Milestone?

Foliar absorption of aminopyralid applied postemergence is relatively rapid. The time required for aminopyralid rainfastness depends on environmental conditions and the species targeted for control. The treatment will be rainfast within two hours after application when applied at labeled rates.

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Can I spray Milestone under trees?

Under normal use rates and conditions, when applied under mature trees, field trials have shown that Milestone will not cause injury to tree species, such as sweetgum, black cherry, poplars, loblolly pine, red maple and ash. Applications under desirable trees should be made so that the spray does not contact the foliage of the trees. Applications under trees can cause some leaf discoloration, curling or other symptoms under some conditions where high rates or overapplication has occurred, on extremely sandy soils and on certain sensitive ornamental trees. Significant injury can be expected from applications of Milestone under leguminous trees, such as black locust, honeylocust and redbud.

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Will plants become resistant to Milestone™ herbicide?

Aminopyralid has an auxinic growth regulator mode of action. Despite extensive use, herbicides with this mode-of-action have demonstrated a low risk of resistance development compared to herbicides with other mode-of-action classifications, such as ALS inhibitors, photosystem II inhibitors or ACCase inhibitors.

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What is the environmental impact of Milestone?

Milestone is registered under the EPA’s Reduced Risk Pesticide initiative. Milestone carries a Caution signal word, and it is not a federally Restricted Use Pesticide, so it does not require a special license for purchase or application. Because of its non-volatile formulation and its low use rates, Milestone provides effective control with reduced exposure for workers and for the environment.

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What is the EPA’s Reduced Risk Pesticide initiative?

Milestone™ herbicide has been reviewed and registered under the Reduced Risk Pesticide initiative of the U.S. Environmental Protection Agency. This unique program is reserved for compounds that demonstrate lower risk to humans and the environment than other available alternatives.

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